For how long are principal investigator records typically required to be retained after completion of a study?

• A. Typically at least 3 years after completion, though institutional policies may vary
• B. Indefinitely
• C. One year
• D. Six months

Answer: (D)

Retention duration for investigator records after a study ends is about ensuring documentation remains available for regulatory review, audits, and any later inquiries about compliance or animal welfare. The typical minimum standard is to keep records for at least three years after completion. This aligns with major guidelines and policies that require a multi-year window to address potential questions, adverse event reviews, or sponsor and regulatory inspections. Institutions may set longer retention times based on accreditation, sponsor requirements, or internal policy, but six months is usually far too short to cover these needs. In short, three years after study completion is the common baseline, with variation by policy.