Who is authorized to perform procedures on animals under approved protocols?

• A. Any staff member regardless of training.
• B. Only the PI.
• C. Only veterinarians.
• D. Personnel listed on the protocol who have completed required training, under supervision of the PI and IACUC.

Answer: (D)

The main idea is that procedures on animals under approved protocols are limited to people who are specifically listed on that protocol and have completed the required training, all performed under supervision of the Principal Investigator and the IACUC. The protocol identifies who is authorized to perform each procedure and the level of training needed, ensuring that work is done by qualified individuals. The PI bears responsibility for the conduct of the study and for ensuring that those procedures are carried out by trained personnel, while IACUC oversight provides ongoing monitoring for welfare and compliance. This arrangement protects animal welfare, maintains data integrity, and aligns with regulatory and ethical requirements. Other options fail because procedures cannot be carried out by anyone regardless of training, nor are they limited solely to the PI or only to veterinarians.